POMC Antikörper (AA 237-267)

Produktnummer ABIN673209

Dieser Anti-POMC Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von POMC in ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Maus und Ratte. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für POMC Antikörper (AA 237-267) (ABIN673209)

Target: POMC (Proopiomelanocortin (POMC))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POMC Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-POMC Antikörper

Bindungsspezifität: AA 237-267

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human POMC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-POMC Antikörper (ABIN673209)

Xie, Wang, Li, Chao, Yue: "Early Repeated Administration of CXCR4 Antagonist AMD3100 Dose-Dependently Improves Neuropathic Pain in Rats After L5 Spinal Nerve Ligation." in: Neurochemical research, Vol. 41, Issue 9, pp. 2289-99, (2016) (PubMed).

Nakamoto, Nishinaka, Sato, Mankura, Koyama, Kasuya, Tokuyama: "Hypothalamic GPR40 signaling activated by free long chain fatty acids suppresses CFA-induced inflammatory chronic pain." in: PLoS ONE, Vol. 8, Issue 12, pp. e81563, (2013) (PubMed).

Chao, Lu, Lee, Chen, Wang, Yang, Cheng, Liao, Ro: "Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury." in: PLoS ONE, Vol. 7, Issue 8, pp. e43680, (2012) (PubMed).

Details zu POMC

Target: POMC (Proopiomelanocortin (POMC))

Andere Bezeichnung: POMC

Hintergrund:

Synonyms: LPH, MSH, NPP, POC, ACTH, CLIP, Pro-opiomelanocortin, POMC, Corticotropin-lipotropin

Background: ACTH stimulates the adrenal glands to release cortisol. MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes. Beta-endorphin and Met-enkephalin are endogenous opiates.

Gen-ID: 5443

UniProt: P01189

Pathways: Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, Feeding Behaviour